E-mail: dzwerschke at igc.gulbenkian.pt
Currently I am the lab manager of the Evolutionary Biology group. On a daily basis I am primarily responsible for a smooth workflow in the lab. As a research assistant my current work focuses on the microbiota, particularly E. coli, in the human gut. I graduated in Biology with the major Genetics, Cell biology and Physiology and obtained a Master’s degree in Genome Based Systems Biology from Bielefeld University, Germany. My thesis was a product of collaboration with the Faculty of Science of Lisbon University (FCUL) and aimed on a deeper understanding of virulence factors in nosocomial bacterial pathogens.
During my work in the past years got more and more caught by the subject of interactions between organisms; especially between different species as seen with microorganisms and their hosts. In the context of our group’s work these interactions can be found in the adaptation of commensal E. coli to the mammalian host. They are dynamic and variable and finding an explanation for what we observe always just seems one step ahead…
Sousa A, Ramiro RS, Barroso-Batista J, Güleresi D, Lourenço M, Gordo I (2017) Recurrent Reverse Evolution Maintains Polymorphism After Strong Bottlenecks in Commensal Gut Bacteria. Molecular Biology and Evolution 34(11):2879-2892. doi: 10.1093/molbev/msx221
Lourenço M, Ramiro RS, Güleresi D, Barroso-Batista J, Xavier KB, Gordo I, et al. (2016) A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut. PLoS Genet 12(11): e1006420. doi: 10.1371/journal.pgen.1006420